INO80C

Across TCGA pan-cancer cohorts, INO80C RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated INO80C data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher INO80C RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated INO80C expression acts as an unfavorable survival marker, although some lineages such as THCA and KIRC show a favorable association.

ACC, LUAD, and UVM are the cancer types where INO80C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.160	0.636	<.001	123	view →
LUAD	DFS	Tertile	III,IV	0.268	0.716	.002	57	view →
UVM	DFS	Tertile	III,IV	0.253	0.856	.004	56	view →
LIHC	DFS	Median	All	0.372	0.495	<.001	54	view →
THCA	DFS	Tertile	All	0.933	0.711	<.001	51	view →
KIRC	OS	Median	All	0.709	0.534	<.001	50	view →
SKCM	OS	Quartile	All	0.210	0.585	<.001	46	view →
CESC	DFS	Median	All	0.841	0.636	<.001	44	view →
UCEC	DFS	Median	All	0.789	0.884	<.001	34	view →
SCLC	DFS	Median	II,III,IV	0.427	0.984	.009	24	view →
KIRP	OS	Median	II,III,IV	0.858	0.620	.007	20	view →
MESO	OS	Median	All	0.446	0.631	.009	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

INO80C–ACC (DFS)

Open the ACC breakdown →