INO80C

Across TCGA patient cohorts, INO80C mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INO80C-associated genes across cancer lineages are RNU6-191P, LINC02729, and CCDC196. Each is linked with INO80C in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80C-to-partner and partner-to-INO80C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-191P grouped by INO80C-low versus INO80C-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80C→partner) and Y-score (partner→INO80C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-191P →	+0.360	+7.731	<.001	.009	3	1
BRCA	LINC02729 →	+0.074	+7.731	<.001	.009	3	1
UCEC	CCDC196 →	+0.288	+3.593	<.001	.006	3	1
UCEC	RNY4P23 →	+0.494	+3.616	<.001	.005	3	1
UCEC	RNU4-17P →	+0.229	+4.400	<.001	.006	3	1
UCEC	RNU6-657P →	+0.303	+4.400	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

RNU6-191P by INO80C expression — BRCA

Explore this box plot interactively →