INO80C

Across TCGA cell cohorts, INO80C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,208 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INO80C-associated GO terms across cancer lineages are Positive regulation of telomere maintenance in response to DNA damage, Regulation of telomere maintenance in response to DNA damage, and DNA-templated DNA replication maintenance of fidelity. Each is linked with INO80C in more than 7 cancer types. Because this analysis shows association rather than direction, both INO80C-to-partner and partner-to-INO80C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere maintenance in response to DNA damage grouped by INO80C-low versus INO80C-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80C→partner) and Y-score (partner→INO80C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of telomere maintenance in response to DNA damage →	+0.091	+0.969	<.001	<.001	3	8
SOFT_TISSUE	Regulation of telomere maintenance in response to DNA damage →	+0.072	+0.629	<.001	<.001	3	7
BLOOD_Lymphoma	DNA-templated DNA replication maintenance of fidelity →	+0.075	+1.028	<.001	<.001	3	7
CNS	Chromosome segregation →	+0.047	+0.536	<.001	<.001	3	7
BLOOD_Leukemia	Positive regulation of mitotic nuclear division →	+0.044	+0.423	.009	.003	3	7
BLOOD_Myeloma	Double-strand break repair via break-induced replication →	+0.119	+0.710	.006	.006	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,208 associations by consensus.

Positive regulation of telomere maintenance in response to DNA damage by INO80C expression — SOFT_TISSUE

Explore this box plot interactively →