INO80C

Across TCGA cell cohorts, INO80C mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible INO80C-associated genes across cancer lineages are OR6B3 and EDDM3A. Each is linked with INO80C in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80C-to-partner and partner-to-INO80C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6B3 grouped by INO80C-low versus INO80C-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80C→partner) and Y-score (partner→INO80C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6B3 →	+0.136	+6.022	<.001	.001	3	1
SKIN	EDDM3A →	+0.029	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR6B3 by INO80C expression — SKIN

Explore this box plot interactively →