INO80B-WBP1

Across TCGA patient cohorts, INO80B-WBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,675 significant associations in total. THCA shows the largest number of these associations.

The most reproducible INO80B-WBP1-associated GO terms across cancer lineages are Mitotic spindle elongation, Regulation of DNA-templated DNA replication, and XMP metabolic process. Each is linked with INO80B-WBP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both INO80B-WBP1-to-partner and partner-to-INO80B-WBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by INO80B-WBP1-low versus INO80B-WBP1-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80B-WBP1→partner) and Y-score (partner→INO80B-WBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Mitotic spindle elongation →	+0.081	+0.107	<.001	<.001	3	15
BLCA	Regulation of DNA-templated DNA replication →	+0.026	+0.042	<.001	<.001	3	15
SARC	XMP metabolic process →	+0.038	+0.073	<.001	<.001	3	15
ACC	Positive regulation of mitotic sister chromatid separation →	+0.079	+0.099	<.001	<.001	3	15
OV	Cell cycle checkpoint signaling →	+0.027	+0.067	<.001	<.001	3	15
ACC	Spindle elongation →	+0.079	+0.113	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,675 associations by consensus.

Mitotic spindle elongation by INO80B-WBP1 expression — ACC

Explore this box plot interactively →