INO80B-WBP1

Across TCGA pan-cancer cohorts, INO80B-WBP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of INO80B-WBP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where INO80B-WBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types INO80B-WBP1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, COAD, and LUSC are the cancer types where INO80B-WBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INO80B-WBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.075	.002	8	view →
COAD	All	All	+0.056	.001	6	view →
LUSC	All	All	+0.063	<.001	5	view →
KICH	Female	II,III,IV	−0.095	<.001	4	view →
THCA	All	All	−0.044	.003	3	view →
BRCA	All	All	+0.029	.017	2	view →
LUAD	Male	All	+0.045	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

INO80B-WBP1–HNSC

Open the HNSC breakdown →