INO80B-WBP1

Across TCGA pan-cancer cohorts, INO80B-WBP1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated INO80B-WBP1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher INO80B-WBP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated INO80B-WBP1 expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRC show a favorable association.

KICH, ACC, and UCS are the cancer types where INO80B-WBP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	All	0.625	1.000	<.001	99	view →
ACC	OS	Median	All	0.768	0.971	<.001	79	view →
UCS	OS	Median	III,IV	0.211	0.686	<.001	76	view →
CESC	OS	Tertile	All	0.860	0.719	.008	40	view →
LUAD	OS	Median	All	0.273	0.445	.003	35	view →
LGG	OS	Quartile	All	0.383	0.633	<.001	27	view →
MESO	OS	Tertile	III,IV	0.461	0.663	.016	25	view →
KIRC	DFS	Quartile	III,IV	0.867	0.465	.001	24	view →
COAD	DFS	Quartile	II,III,IV	0.504	0.727	.007	21	view →
READ	DFS	Tertile	IV	0.362	0.770	.019	14	view →
LUSC	OS	Quartile	All	0.534	0.357	.004	14	view →
THCA	OS	Tertile	All	0.915	1.000	.013	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

INO80B-WBP1–KICH (OS)

Open the KICH breakdown →