INO80

Across TCGA cell cohorts, INO80 mutation is significantly associated with the RNA expression of many other genes, with 223 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INO80-associated genes across cancer lineages are FABP12, IFNA8, and ASZ1. Each is linked with INO80 in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80-to-partner and partner-to-INO80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP12 grouped by INO80-low versus INO80-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80→partner) and Y-score (partner→INO80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	FABP12 →	+0.080	+4.237	<.001	.006	3	2
LUNG_SCLC	IFNA8 →	+0.053	+4.169	<.001	.001	3	2
BLOOD_Lymphoma	ASZ1 →	+1.091	+3.421	.001	.007	3	2
BLOOD_Lymphoma	KRTAP9-1 →	+0.022	+3.925	<.001	.006	3	2
BLOOD_Leukemia	CPXCR1 →	+0.046	+2.471	.001	.001	3	2
BLOOD_Leukemia	SIVA1 →	+0.718	+3.215	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 223 associations by consensus.

FABP12 by INO80 expression — PANCREAS

Explore this box plot interactively →