INHBB

Across TCGA patient cohorts, INHBB mutation is significantly associated with the RNA expression of many other genes, with 3,648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INHBB-associated genes across cancer lineages are MIR6803, RN7SL346P, and ZFYVE19. Each is linked with INHBB in more than 2 cancer types. Because this analysis shows association rather than direction, both INHBB-to-partner and partner-to-INHBB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by INHBB-low versus INHBB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBB→partner) and Y-score (partner→INHBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.137	+4.308	<.001	.003	3	3
BLCA	RN7SL346P →	+0.187	+4.533	.001	.005	3	3
UCEC	ZFYVE19 →	+0.431	+3.831	.001	<.001	3	2
UCEC	SF1 →	+0.428	+3.480	<.001	.002	3	2
UCEC	LETM1 →	+0.502	+3.716	<.001	<.001	3	2
UCEC	EDC4 →	+0.718	+2.914	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,648 associations by consensus.

MIR6803 by INHBB expression — UCEC

Explore this box plot interactively →