INHBB

Across TCGA pan-cancer cohorts, INHBB RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of INHBB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where INHBB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types INHBB is over-expressed in tumor, although a few such as BRCA and BLCA show the opposite, repressed pattern.

KIRC, COAD, and THCA are the cancer types where INHBB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INHBB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+3.889	<.001	12	view →
COAD	All	IV	+1.799	<.001	11	view →
THCA	Male	All	+1.307	<.001	10	view →
BRCA	All	II,III,IV	−1.407	<.001	6	view →
KIRP	All	IV	+1.330	.009	6	view →
BLCA	All	All	−1.149	.001	6	view →
HNSC	All	III,IV	+1.021	.005	6	view →
STAD	Male	All	+1.144	.001	4	view →
KICH	Female	All	+0.932	.019	3	view →
LUAD	All	All	+0.647	.002	3	view →
READ	All	All	+2.492	.006	2	view →
PRAD	All	All	+0.620	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

INHBB–KIRC

Open the KIRC breakdown →