Across TCGA patient cohorts, IMPDH1P2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IMPDH1P2-associated genes across cancer lineages are MIR6089, OR2AP1, and RNA5SP389. Each is linked with IMPDH1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IMPDH1P2-to-partner and partner-to-IMPDH1P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPDH1P2→partner) and Y-score (partner→IMPDH1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6089 →	+1.323	+5.937	<.001	.002	3	1
UCEC	OR2AP1 →	+0.182	+5.852	<.001	.003	3	1
UCEC	RNA5SP389 →	+1.518	+5.031	<.001	.009	3	1
UCEC	RNU4-58P →	+0.725	+5.133	<.001	.008	3	1
UCEC	RNU6-271P →	+0.918	+5.852	<.001	.003	3	1
UCEC	RNA5SP72 →	+0.817	+5.031	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

IMPDH1P2 survival (RNA) · tumor vs normal (RNA) · all IMPDH1P2 data types