IL7R

Across TCGA cell cohorts, IL7R RNA expression is significantly associated with the go_rna of many other GO terms, with 6,027 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL7R-associated GO terms across cancer lineages are Regulation of fibroblast proliferation, Positive regulation of supramolecular fiber organization, and Pyrimidine-containing compound transmembrane transport. Each is linked with IL7R in more than 13 cancer types. Because this analysis shows association rather than direction, both IL7R-to-partner and partner-to-IL7R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast proliferation grouped by IL7R-low versus IL7R-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL7R→partner) and Y-score (partner→IL7R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of fibroblast proliferation →	+0.128	+1.760	<.001	.008	3	14
LIVER	Positive regulation of supramolecular fiber organization →	+0.098	+3.066	.003	.002	3	14
LIVER	Pyrimidine-containing compound transmembrane transport →	-0.238	-2.728	.001	<.001	3	14
BREAST	Coagulation →	+0.115	+1.460	<.001	.002	3	13
LIVER	Caveola assembly →	+0.225	+2.098	.003	.002	3	13
BREAST	Blood coagulation →	+0.116	+1.460	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,027 associations by consensus.

Regulation of fibroblast proliferation by IL7R expression — PANCREAS

Explore this box plot interactively →