IL36RN

Across TCGA cell cohorts, IL36RN RNA expression is significantly associated with the RNA expression of many other genes, with 3,878 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible IL36RN-associated genes across cancer lineages are IL1F10, IL1RN, and NECTIN4. Each is linked with IL36RN in more than 8 cancer types. Because this analysis shows association rather than direction, both IL36RN-to-partner and partner-to-IL36RN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL36RN versus IL1F10 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL36RN→partner) and Y-score (partner→IL36RN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	IL1F10 →	+0.271	+1.169	<.001	<.001	3	9
PANCREAS	IL1RN →	+3.251	+0.714	<.001	<.001	3	9
OVARY	NECTIN4 →	+3.461	+1.125	<.001	<.001	3	8
OESOPHAGUS	IVL →	+2.845	+1.428	<.001	<.001	3	7
PANCREAS	CRYBG2 →	+2.491	+0.640	<.001	<.001	3	7
URINARY_TRACT	GRHL1 →	+2.283	+1.214	<.001	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,878 associations by consensus.

IL36RN vs IL1F10 — UPPER_AERODIGESTIVE_TRACT

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