IL33

Across TCGA patient cohorts, IL33 protein abundance is significantly associated with the RNA expression of many other genes, with 19,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL33-associated genes across cancer lineages are CLEC3B, C7, and MMRN1. Each is linked with IL33 in more than 8 cancer types. Because this analysis shows association rather than direction, both IL33-to-partner and partner-to-IL33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL33 versus CLEC3B in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL33→partner) and Y-score (partner→IL33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLEC3B →	+1.371	+1.015	<.001	<.001	3	9
OV	C7 →	+2.540	+0.729	.004	.003	3	8
CCRCC	MMRN1 →	+1.358	+0.550	<.001	<.001	3	8
UCEC	ABCA8 →	+1.261	+0.908	<.001	<.001	3	8
HNSC	ABCA6 →	+1.059	+0.826	<.001	<.001	3	8
CCRCC	JAM2 →	+0.856	+0.614	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,032 associations by consensus.

IL33 vs CLEC3B — BRCA

Explore this scatter interactively →