IL33

Across TCGA cell cohorts, IL33 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,520 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL33-associated GO terms across cancer lineages are Response to vitamin E, Host-mediated modulation of intestinal microbiota composition, and Alcohol metabolic process. Each is linked with IL33 in more than 4 cancer types. Because this analysis shows association rather than direction, both IL33-to-partner and partner-to-IL33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to vitamin E grouped by IL33-low versus IL33-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL33→partner) and Y-score (partner→IL33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to vitamin E →	+0.156	+0.316	.001	.004	3	4
LARGE_INTESTINE	Host-mediated modulation of intestinal microbiota composition →	+1.130	+2.231	<.001	<.001	3	4
LARGE_INTESTINE	Alcohol metabolic process →	+0.034	+2.443	<.001	<.001	3	4
LARGE_INTESTINE	Fatty acid beta-oxidation →	+0.095	+3.190	<.001	<.001	3	4
LARGE_INTESTINE	Metanephric glomerular mesangium development →	-1.059	-2.685	<.001	<.001	3	4
LARGE_INTESTINE	Olefinic compound metabolic process →	+0.072	+3.219	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,520 associations by consensus.

Response to vitamin E by IL33 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →