IL31RA

Across TCGA cell cohorts, IL31RA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,968 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IL31RA-associated GO terms across cancer lineages are PML body organization, Positive regulation of focal adhesion assembly, and Positive regulation of cell-substrate junction organization. Each is linked with IL31RA in more than 12 cancer types. Because this analysis shows association rather than direction, both IL31RA-to-partner and partner-to-IL31RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by IL31RA-low versus IL31RA-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL31RA→partner) and Y-score (partner→IL31RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PML body organization →	+0.261	+1.937	<.001	.001	3	13
BREAST	Positive regulation of focal adhesion assembly →	+0.206	+1.209	<.001	<.001	3	13
BONE	Positive regulation of cell-substrate junction organization →	+0.162	+1.598	<.001	<.001	3	13
BREAST	Positive regulation of supramolecular fiber organization →	+0.101	+0.995	<.001	.001	3	13
SOFT_TISSUE	Urokinase plasminogen activator signaling pathway →	+0.724	+1.328	<.001	<.001	3	12
BREAST	Positive regulation of extracellular matrix disassembly →	+0.207	+1.014	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,968 associations by consensus.

PML body organization by IL31RA expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →