IL31

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL31 mutation is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL31-associated genes across cancer lineages are USP9YP10, RN7SL325P, and USP9YP2. Each is linked with IL31 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL31-to-partner and partner-to-IL31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL31→partner) and Y-score (partner→IL31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LGGUSP9YP10 →+0.049+7.977<.001.00732
UCECRN7SL325P →+0.170+3.505<.001.00532
UCECUSP9YP2 →+0.040+6.481<.001<.00132
SKCMCCDC34P1 →+0.057+4.199<.001.00932
BLCADEFB117 →+0.186+4.562.001.00632
READPGBD4P2 →+0.162+6.257<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

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