IL26

Across TCGA patient cohorts, IL26 mutation is significantly associated with the RNA expression of many other genes, with 362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL26-associated genes across cancer lineages are FAM204DP, MIR5692C1, and UBE2V1P4. Each is linked with IL26 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL26-to-partner and partner-to-IL26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM204DP grouped by IL26-low versus IL26-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL26→partner) and Y-score (partner→IL26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FAM204DP →	+0.213	+4.993	<.001	.002	3	2
SKCM	MIR5692C1 →	+0.452	+4.743	<.001	.005	3	2
CESC	UBE2V1P4 →	+0.144	+5.103	<.001	.008	3	2
COAD	ATP6V1E1P2 →	+0.437	+4.611	<.001	.004	3	2
COAD	POLR3KP2 →	+0.321	+5.003	<.001	.004	3	2
CESC	LACRT →	+0.078	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

FAM204DP by IL26 expression — COAD

Explore this box plot interactively →