IL23R

Across TCGA patient cohorts, IL23R RNA expression is significantly associated with the protein abundance of many other proteins, with 10,154 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IL23R-associated proteins across cancer lineages are DOCK11, IKZF1_S445, and LCP1. Each is linked with IL23R in more than 5 cancer types. Because this analysis shows association rather than direction, both IL23R-to-partner and partner-to-IL23R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL23R versus DOCK11 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL23R→partner) and Y-score (partner→IL23R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DOCK11 →	+0.462	+0.125	<.001	<.001	3	6
LUAD	IKZF1_S445 →	+1.186	+0.471	.004	.001	3	6
GBM	LCP1 →	+0.779	+0.056	<.001	.008	3	6
LSCC	SAMHD1 →	+0.596	+0.384	<.001	.002	3	6
LSCC	RASAL3 →	+0.424	+0.277	<.001	<.001	3	6
HNSC	EVL →	+0.736	+0.532	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,154 associations by consensus.

IL23R vs DOCK11 — BRCA

Explore this scatter interactively →