IL23R

Across TCGA cell cohorts, IL23R RNA expression is significantly associated with the go_rna of many other GO terms, with 1,978 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL23R-associated GO terms across cancer lineages are Renal D-glucose absorption, Membrane bending, and Prolactin signaling pathway. Each is linked with IL23R in more than 4 cancer types. Because this analysis shows association rather than direction, both IL23R-to-partner and partner-to-IL23R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal D-glucose absorption grouped by IL23R-low versus IL23R-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL23R→partner) and Y-score (partner→IL23R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Renal D-glucose absorption →	+1.358	+0.224	<.001	<.001	3	4
STOMACH	Membrane bending →	+0.167	+0.132	.003	.001	2	5
LARGE_INTESTINE	Prolactin signaling pathway →	-0.261	-0.207	<.001	<.001	3	4
BLOOD_Lymphoma	Regulation of lipid biosynthetic process →	+0.028	+0.851	.007	.002	3	4
BLOOD_Lymphoma	Positive regulation of nitric-oxide synthase activity →	+0.400	+1.151	.003	.002	3	4
BLOOD_Lymphoma	Mononuclear cell migration →	+0.141	+1.127	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,978 associations by consensus.

Renal D-glucose absorption by IL23R expression — LARGE_INTESTINE

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