IL20

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL20 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,879 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IL20-associated proteins across cancer lineages are LDLRAP1, NEDD4, and LUZP1. Each is linked with IL20 in more than 3 cancer types. Because this analysis shows association rather than direction, both IL20-to-partner and partner-to-IL20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL20 versus LDLRAP1 in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL20→partner) and Y-score (partner→IL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLDLRAP1 →+0.438+0.114<.001<.00134
UCECNEDD4 →+0.429+0.542<.001.00333
HNSCLUZP1 →+0.232+1.086<.001<.00133
HNSCALDH5A1 →-0.558-1.505<.001<.00133
UCECLIMS1 →+0.427+0.560<.001.00233
LSCCDCHS1 →+0.426+0.650<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,879 associations by consensus.

IL20 vs LDLRAP1 — GBM

Per-sample scatter of IL20 vs LDLRAP1 in GBM (Pearson r = 0.33).

Explore this scatter interactively →

Exploration