IL17RE

Across TCGA cell cohorts, IL17RE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,752 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL17RE-associated GO terms across cancer lineages are Cellular response to indole-3-methanol, Regulation of blood-brain barrier permeability, and Response to indole-3-methanol. Each is linked with IL17RE in more than 11 cancer types. Because this analysis shows association rather than direction, both IL17RE-to-partner and partner-to-IL17RE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to indole-3-methanol grouped by IL17RE-low versus IL17RE-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RE→partner) and Y-score (partner→IL17RE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.189	+2.335	<.001	<.001	3	12
STOMACH	Regulation of blood-brain barrier permeability →	+0.226	+2.247	.001	<.001	3	11
URINARY_TRACT	Response to indole-3-methanol →	+0.223	+2.185	<.001	<.001	3	11
URINARY_TRACT	NMDA selective glutamate receptor signaling pathway →	+0.269	+1.797	<.001	<.001	3	10
STOMACH	Positive regulation of sodium ion transport →	+0.227	+2.357	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.047	+1.194	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,752 associations by consensus.

Cellular response to indole-3-methanol by IL17RE expression — URINARY_TRACT

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