IL17RB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL17RB protein abundance is significantly associated with the RNA expression of many other genes, with 705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL17RB-associated genes across cancer lineages are CCN4, CDK6, and CPZ. Each is linked with IL17RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17RB-to-partner and partner-to-IL17RB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL17RB versus CCN4 in GBM, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RB→partner) and Y-score (partner→IL17RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCCN4 →-1.382-0.478.006.00131
GBMCDK6 →-1.303-0.374<.001<.00131
GBMCPZ →-0.352-0.509.003.00331
GBMSATB2 →-1.043-0.460.001.00531
GBMFAM117A →-0.627-0.471<.001<.00131
GBMEXTL3 →-1.019-0.466<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

IL17RB vs CCN4 — GBM

Per-sample scatter of IL17RB vs CCN4 in GBM (Pearson r = -0.42).

Explore this scatter interactively →

Exploration