IL17RB

Across TCGA patient cohorts, IL17RB mutation is significantly associated with the RNA expression of many other genes, with 1,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL17RB-associated genes across cancer lineages are RNU6-13P, RNU6-756P, and LINC01943. Each is linked with IL17RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17RB-to-partner and partner-to-IL17RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by IL17RB-low versus IL17RB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RB→partner) and Y-score (partner→IL17RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-13P →	+0.454	+4.893	<.001	.005	3	2
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	2
UCEC	LINC01943 →	+0.477	+1.939	.001	.009	3	1
UCEC	PANDAR →	+0.023	+2.139	.009	.005	3	1
SKCM	RNA5SP166 →	+0.328	+7.816	<.001	.008	3	1
BRCA	KRTAP19-4 →	+0.098	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,844 associations by consensus.

RNU6-13P by IL17RB expression — COAD

Explore this box plot interactively →