IL13RA2

Across TCGA patient cohorts, IL13RA2 mutation is significantly associated with the RNA expression of many other genes, with 913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL13RA2-associated genes across cancer lineages are MIR6765, URGCP-MRPS24, and NDUFAF1. Each is linked with IL13RA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IL13RA2-to-partner and partner-to-IL13RA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6765 grouped by IL13RA2-low versus IL13RA2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL13RA2→partner) and Y-score (partner→IL13RA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR6765 →	+0.587	+3.748	<.001	.008	3	3
UCEC	URGCP-MRPS24 →	+0.259	+2.406	<.001	<.001	3	3
UCEC	NDUFAF1 →	+0.406	+2.180	.003	.002	3	3
LIHC	RPL12P48 →	+0.107	+5.033	<.001	.009	3	2
UCEC	MAP3K4-AS1 →	+0.707	+2.721	<.001	.003	3	2
UCEC	RN7SL248P →	+0.056	+3.059	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 913 associations by consensus.

MIR6765 by IL13RA2 expression — LUSC

Explore this box plot interactively →