IL13RA2

Across TCGA cell cohorts, IL13RA2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL13RA2-associated genes across cancer lineages are KHDC3L, RIT2, and ADIG. Each is linked with IL13RA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL13RA2-to-partner and partner-to-IL13RA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KHDC3L grouped by IL13RA2-low versus IL13RA2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL13RA2→partner) and Y-score (partner→IL13RA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KHDC3L →	+0.028	+4.215	<.001	.002	3	1
LARGE_INTESTINE	RIT2 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ADIG →	+0.038	+4.977	<.001	.007	3	1
LARGE_INTESTINE	NME8 →	+0.586	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KHDC3L by IL13RA2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →