IGSF5

Across TCGA patient cohorts, IGSF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,353 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGSF5-associated proteins across cancer lineages are CROCC, ADH5, and PRXL2B. Each is linked with IGSF5 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGSF5-to-partner and partner-to-IGSF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF5 versus CROCC in UCEC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF5→partner) and Y-score (partner→IGSF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CROCC →	+0.495	+0.917	<.001	<.001	3	5
OV	ADH5 →	+0.405	+0.279	.001	.001	3	4
GBM	PRXL2B →	+0.310	+0.577	.009	.008	3	3
OV	CKAP4_S26 →	-0.756	-0.218	.004	.005	3	3
PDAC	HMGA1_T53 →	-0.801	-0.729	<.001	<.001	3	3
PDAC	RHBDF2_S385 →	-0.660	-0.546	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,353 associations by consensus.

IGSF5 vs CROCC — UCEC

Explore this scatter interactively →