IGSF5

Across TCGA cell cohorts, IGSF5 RNA expression is significantly associated with the RNA expression of many other genes, with 6,397 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IGSF5-associated genes across cancer lineages are B3GALT5, PCP4, and DENND6B. Each is linked with IGSF5 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGSF5-to-partner and partner-to-IGSF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF5 versus B3GALT5 in PANCREAS, with a Pearson correlation of 0.78.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF5→partner) and Y-score (partner→IGSF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	B3GALT5 →	+2.986	+0.696	<.001	<.001	3	10
BREAST	PCP4 →	+3.326	+0.895	<.001	<.001	3	5
BREAST	DENND6B →	+1.452	+0.832	<.001	<.001	3	4
BREAST	PRR15L →	+2.795	+0.586	<.001	<.001	3	4
BREAST	FAIM2 →	+1.416	+0.826	<.001	<.001	3	4
BREAST	FAM214A →	+1.572	+0.820	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,397 associations by consensus.

IGSF5 vs B3GALT5 — PANCREAS

Explore this scatter interactively →