IGLVI-70

Across TCGA patient cohorts, IGLVI-70 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,864 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLVI-70-associated GO terms across cancer lineages are Complement activation, Complement activation, classical pathway, and B cell mediated immunity. Each is linked with IGLVI-70 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGLVI-70-to-partner and partner-to-IGLVI-70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Complement activation grouped by IGLVI-70-low versus IGLVI-70-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVI-70→partner) and Y-score (partner→IGLVI-70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Complement activation →	+0.137	+0.912	<.001	<.001	3	28
THCA	Complement activation, classical pathway →	+0.173	+0.911	<.001	<.001	3	28
ESCA	B cell mediated immunity →	+0.109	+0.904	<.001	<.001	3	28
THCA	Antibacterial humoral response →	+0.152	+0.941	<.001	<.001	3	28
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.146	+0.913	<.001	<.001	3	28
ESCA	CD4-positive, alpha-beta T cell differentiation →	+0.069	+0.711	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,864 associations by consensus.

Complement activation by IGLVI-70 expression — THCA

Explore this box plot interactively →