IGLVI-70

Across TCGA pan-cancer cohorts, IGLVI-70 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of IGLVI-70’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where IGLVI-70 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGLVI-70 is over-expressed in tumor, although a few such as BRCA and READ show the opposite, repressed pattern.

LUAD, KIRC, and BRCA are the cancer types where IGLVI-70 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGLVI-70 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+1.296	<.001	8	view →
KIRC	All	All	+0.419	.003	5	view →
BRCA	Female	II,III,IV	−0.358	.027	4	view →
READ	All	All	−1.165	.004	3	view →
COAD	All	All	−0.943	.020	2	view →
STAD	All	IV	−1.916	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

IGLVI-70–LUAD

Open the LUAD breakdown →