IGLV8OR8-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV8OR8-1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV8OR8-1-associated genes across cancer lineages are MIR520H, COPS8P1, and NIPA2P3. Each is linked with IGLV8OR8-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV8OR8-1-to-partner and partner-to-IGLV8OR8-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV8OR8-1→partner) and Y-score (partner→IGLV8OR8-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR520H →+0.483+4.997<.001.00332
UCECCOPS8P1 →+0.148+3.748<.001.00831
UCECNIPA2P3 →+0.084+4.997.009.00331
SKCMRNU6-344P →+0.296+5.199<.001.00331
SKCMLINC02304 →+0.117+5.624<.001.00231
SKCMRARRES2P5 →+0.221+4.500<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

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