IGLV7-35

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV7-35 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV7-35-associated genes across cancer lineages are RNU6-591P. Each is linked with IGLV7-35 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV7-35-to-partner and partner-to-IGLV7-35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by IGLV7-35-low versus IGLV7-35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV7-35→partner) and Y-score (partner→IGLV7-35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-591P →+0.652+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RNU6-591P by IGLV7-35 expression — UCEC

Box plot of RNU6-591P in IGLV7-35-low vs IGLV7-35-high samples in UCEC.

Explore this box plot interactively →

Exploration