Across TCGA patient cohorts, IGLV3-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,171 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLV3-4-associated GO terms across cancer lineages are B cell mediated immunity, Antigen receptor-mediated signaling pathway, and Regulation of B cell activation. Each is linked with IGLV3-4 in more than 14 cancer types. Because this analysis shows association rather than direction, both IGLV3-4-to-partner and partner-to-IGLV3-4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-4→partner) and Y-score (partner→IGLV3-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	B cell mediated immunity →	+0.101	+0.146	<.001	<.001	3	15
STAD	Antigen receptor-mediated signaling pathway →	+0.101	+0.109	<.001	<.001	3	14
STAD	Regulation of B cell activation →	+0.094	+0.109	<.001	<.001	3	14
STAD	B cell differentiation →	+0.092	+0.114	<.001	<.001	3	14
STAD	B cell activation →	+0.097	+0.123	<.001	<.001	3	14
STAD	Regulation of leukocyte apoptotic process →	+0.096	+0.112	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,171 associations by consensus.

Exploration

IGLV3-4 survival (RNA) · tumor vs normal (RNA) · all IGLV3-4 data types