IGLV3-29

Across TCGA patient cohorts, IGLV3-29 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,537 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLV3-29-associated GO terms across cancer lineages are Antibacterial humoral response, Complement activation, and Complement activation, classical pathway. Each is linked with IGLV3-29 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGLV3-29-to-partner and partner-to-IGLV3-29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antibacterial humoral response grouped by IGLV3-29-low versus IGLV3-29-high in SARC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-29→partner) and Y-score (partner→IGLV3-29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	Antibacterial humoral response →	+0.131	+0.372	<.001	<.001	3	28
THCA	Complement activation →	+0.117	+0.543	<.001	<.001	3	27
THCA	Complement activation, classical pathway →	+0.150	+0.551	<.001	<.001	3	27
GBM	Antimicrobial humoral response →	+0.110	+0.049	<.001	.005	3	27
ESCA	B cell mediated immunity →	+0.089	+0.533	<.001	<.001	3	26
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.125	+0.551	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,537 associations by consensus.

Antibacterial humoral response by IGLV3-29 expression — SARC

Explore this box plot interactively →