IGLV3-29

Across TCGA pan-cancer cohorts, IGLV3-29 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of IGLV3-29’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where IGLV3-29 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGLV3-29 is over-expressed in tumor, although a few such as KICH and READ show the opposite, repressed pattern.

LUAD, KICH, and READ are the cancer types where IGLV3-29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGLV3-29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+1.004	<.001	7	view →
KICH	Female	All	−0.369	<.001	4	view →
READ	All	All	−0.957	.011	3	view →
KIRC	All	All	+0.258	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

IGLV3-29–LUAD

Open the LUAD breakdown →