Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGLV2-18 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGLV2-18-associated genes across cancer lineages are DEFB108B, SSXP10, and SNORD111B. Each is linked with IGLV2-18 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV2-18-to-partner and partner-to-IGLV2-18 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGLV2-18→partner) and Y-score (partner→IGLV2-18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.