IGLV1-62

Across TCGA patient cohorts, IGLV1-62 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,907 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLV1-62-associated GO terms across cancer lineages are Regulation of CD4-positive, alpha-beta T cell differentiation, B cell receptor signaling pathway, and B cell mediated immunity. Each is linked with IGLV1-62 in more than 23 cancer types. Because this analysis shows association rather than direction, both IGLV1-62-to-partner and partner-to-IGLV1-62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of CD4-positive, alpha-beta T cell differentiation grouped by IGLV1-62-low versus IGLV1-62-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-62→partner) and Y-score (partner→IGLV1-62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of CD4-positive, alpha-beta T cell differentiation →	+0.051	+0.236	<.001	<.001	3	24
ESCA	B cell receptor signaling pathway →	+0.100	+0.249	<.001	<.001	3	24
THCA	B cell mediated immunity →	+0.086	+0.245	<.001	<.001	3	23
THCA	Antibacterial humoral response →	+0.136	+0.222	<.001	<.001	3	23
ESCA	Regulation of CD4-positive, alpha-beta T cell activation →	+0.062	+0.231	<.001	<.001	3	23
STAD	Immunoglobulin production →	+0.079	+0.346	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,907 associations by consensus.

Regulation of CD4-positive, alpha-beta T cell differentiation by IGLV1-62 expression — STAD

Explore this box plot interactively →