Across TCGA patient cohorts, IGLL3P mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLL3P-associated genes across cancer lineages are CYP2C19, MIR6842, and RN7SL495P. Each is linked with IGLL3P in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLL3P-to-partner and partner-to-IGLL3P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL3P→partner) and Y-score (partner→IGLL3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYP2C19 →	+0.080	+4.211	<.001	.009	3	1
UCEC	MIR6842 →	+0.634	+5.722	<.001	.001	3	1
UCEC	RN7SL495P →	+0.234	+5.335	<.001	.003	3	1
BLCA	CYP3A54P →	+0.413	+7.640	<.001	.009	3	1
UCEC	MIR5707 →	+0.710	+5.027	<.001	.004	3	1
UCEC	LINC02079 →	+0.211	+5.226	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

IGLL3P survival (RNA) · tumor vs normal (RNA) · all IGLL3P data types