Across TCGA pan-cancer cohorts, IGLL3P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated IGLL3P data layer compared with 1 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IGLL3P RNA is associated with better overall survival. In most high-consensus cancer types, elevated IGLL3P expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.
HNSC, KIRC, and CESC are the cancer types where IGLL3P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.