Across TCGA patient cohorts, IGLC7 protein abundance is significantly associated with the RNA expression of many other genes, with 8,363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLC7-associated genes across cancer lineages are IGLV6-57, IGLV3-9, and IGHG4. Each is linked with IGLC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGLC7-to-partner and partner-to-IGLC7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC7→partner) and Y-score (partner→IGLC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGLV6-57 →	+2.695	+0.866	<.001	.007	3	4
OV	IGLV3-9 →	+1.656	+0.803	.001	.005	3	4
OV	IGHG4 →	+2.289	+1.224	.002	.001	3	4
OV	IGHV4-34 →	+1.848	+0.759	<.001	.008	3	4
LSCC	ST6GAL1 →	+0.666	+0.710	<.001	<.001	3	3
LSCC	FCRL5 →	+1.169	+0.988	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,363 associations by consensus.

Exploration

IGLC7 survival (RNA) · tumor vs normal (RNA) · all IGLC7 data types