IGKV6D-21

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV6D-21 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,915 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV6D-21-associated proteins across cancer lineages are MZB1, CD38, and HCLS1. Each is linked with IGKV6D-21 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGKV6D-21-to-partner and partner-to-IGKV6D-21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV6D-21→partner) and Y-score (partner→IGKV6D-21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMZB1 →+1.438+0.465<.001.00139
BRCACD38 →+0.919+1.901<.001<.00137
GBMHCLS1 →+0.727+0.297<.001.00637
GBMPLCG2 →+0.512+0.426<.001.00637
BRCAUBE2J1 →+0.589+2.125<.001<.00137
OVGIMAP7 →+0.692+1.836<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,915 associations by consensus.

Exploration