IGKV3OR2-268

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV3OR2-268 protein abundance is significantly associated with the RNA expression of many other genes, with 1,315 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV3OR2-268-associated genes across cancer lineages are IGHV4-31, S100A10, and CD209. Each is linked with IGKV3OR2-268 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGKV3OR2-268-to-partner and partner-to-IGKV3OR2-268 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV3OR2-268 versus IGHV4-31 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV3OR2-268→partner) and Y-score (partner→IGKV3OR2-268) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAIGHV4-31 →+2.760+1.122<.001<.00133
LSCCS100A10 →-1.794-1.765.006.00132
BRCACD209 →+1.183+1.138.002<.00132
PDACCD200R1 →+0.675+0.596.001.00132
LSCCAICDA →+0.297+1.148.003<.00132
LSCCKLRB1 →+1.315+1.635.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,315 associations by consensus.

IGKV3OR2-268 vs IGHV4-31 — BRCA

Per-sample scatter of IGKV3OR2-268 vs IGHV4-31 in BRCA (Pearson r = 0.42).

Explore this scatter interactively →

Exploration