IGKV3-11

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV3-11 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGKV3-11-associated genes across cancer lineages are Smooth muscle. Each is linked with IGKV3-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV3-11-to-partner and partner-to-IGKV3-11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Smooth muscle grouped by IGKV3-11-low versus IGKV3-11-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV3-11→partner) and Y-score (partner→IGKV3-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSmooth muscle →+0.162+3.006.010.02021
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Smooth muscle by IGKV3-11 expression — SKCM

Box plot of Smooth muscle in IGKV3-11-low vs IGKV3-11-high samples in SKCM.

Explore this box plot interactively →

Exploration