IGKV2OR2-10

Across TCGA patient cohorts, IGKV2OR2-10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,128 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV2OR2-10-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Antibacterial humoral response. Each is linked with IGKV2OR2-10 in more than 20 cancer types. Because this analysis shows association rather than direction, both IGKV2OR2-10-to-partner and partner-to-IGKV2OR2-10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGKV2OR2-10-low versus IGKV2OR2-10-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2OR2-10→partner) and Y-score (partner→IGKV2OR2-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.114	+0.137	<.001	<.001	3	21
THCA	Immunoglobulin production →	+0.085	+0.137	<.001	<.001	3	19
THCA	Antibacterial humoral response →	+0.165	+0.127	<.001	<.001	3	18
SARC	Regulation of leukocyte apoptotic process →	+0.076	+0.062	<.001	<.001	3	17
LIHC	Regulation of B cell proliferation →	+0.066	+0.027	<.001	<.001	3	17
SARC	B cell receptor signaling pathway →	+0.094	+0.051	<.001	.009	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,128 associations by consensus.

B cell mediated immunity by IGKV2OR2-10 expression — THCA

Explore this box plot interactively →