IGKV2OR2-1

Across TCGA patient cohorts, IGKV2OR2-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,753 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV2OR2-1-associated GO terms across cancer lineages are Antimicrobial humoral response, Regulation of B cell activation, and B cell mediated immunity. Each is linked with IGKV2OR2-1 in more than 26 cancer types. Because this analysis shows association rather than direction, both IGKV2OR2-1-to-partner and partner-to-IGKV2OR2-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antimicrobial humoral response grouped by IGKV2OR2-1-low versus IGKV2OR2-1-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2OR2-1→partner) and Y-score (partner→IGKV2OR2-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Antimicrobial humoral response →	+0.111	+0.806	<.001	<.001	3	27
ESCA	Regulation of B cell activation →	+0.058	+0.231	<.001	<.001	3	26
ESCA	B cell mediated immunity →	+0.094	+0.330	<.001	<.001	3	26
THCA	Antibacterial humoral response →	+0.166	+0.788	<.001	<.001	3	26
ESCA	Immunoglobulin production →	+0.078	+0.349	<.001	<.001	3	26
CHOL	B cell receptor signaling pathway →	+0.100	+1.183	<.001	.001	2	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,753 associations by consensus.

Antimicrobial humoral response by IGKV2OR2-1 expression — THCA

Explore this box plot interactively →