IGKV2D-30

Across TCGA patient cohorts, IGKV2D-30 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,769 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV2D-30-associated proteins across cancer lineages are MZB1, CD38, and IL16. Each is linked with IGKV2D-30 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV2D-30-to-partner and partner-to-IGKV2D-30 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV2D-30 versus MZB1 in GBM, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-30→partner) and Y-score (partner→IGKV2D-30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MZB1 →	+1.524	+0.214	<.001	.004	3	10
HNSC	CD38 →	+1.002	+1.540	<.001	<.001	3	9
OV	IL16 →	+0.721	+2.538	<.001	<.001	3	8
LSCC	TXNDC5 →	+0.654	+1.593	<.001	<.001	3	8
HNSC	SEC11C →	+1.295	+1.651	<.001	<.001	3	8
HNSC	IRF4 →	+1.020	+1.595	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,769 associations by consensus.

IGKV2D-30 vs MZB1 — GBM

Explore this scatter interactively →