IGKV2D-23

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, IGKV2D-23 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of IGKV2D-23’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where IGKV2D-23 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGKV2D-23 is over-expressed in tumor.

THCA are the cancer types where IGKV2D-23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGKV2D-23 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAFemaleAll+0.040.0442view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

IGKV2D-23–THCA

Tumor-vs-normal expression box plot for IGKV2D-23 RNA in THCA.

Open the THCA breakdown →

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