IGKV2-29

Across TCGA patient cohorts, IGKV2-29 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,474 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IGKV2-29-associated proteins across cancer lineages are IGKV2D-29, MZB1, and GIMAP7. Each is linked with IGKV2-29 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGKV2-29-to-partner and partner-to-IGKV2-29 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV2-29 versus IGKV2D-29 in PDAC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2-29→partner) and Y-score (partner→IGKV2-29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	IGKV2D-29 →	+0.977	+3.958	<.001	<.001	3	9
UCEC	MZB1 →	+1.244	+1.519	<.001	<.001	3	8
OV	GIMAP7 →	+0.605	+1.168	<.001	.006	3	7
COAD	IGHG1 →	+0.779	+2.740	<.001	<.001	3	7
OV	RCSD1 →	+0.617	+1.426	<.001	.004	3	6
BRCA	UBE2J1 →	+0.409	+1.435	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,474 associations by consensus.

IGKV2-29 vs IGKV2D-29 — PDAC

Explore this scatter interactively →