IGKV2-24

Across TCGA patient cohorts, IGKV2-24 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGKV2-24-associated genes across cancer lineages are Megakaryocytes. Each is linked with IGKV2-24 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV2-24-to-partner and partner-to-IGKV2-24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocytes grouped by IGKV2-24-low versus IGKV2-24-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2-24→partner) and Y-score (partner→IGKV2-24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Megakaryocytes →	+0.017	+3.443	.024	.013	3	2

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Megakaryocytes by IGKV2-24 expression — LUAD

Explore this box plot interactively →