IGKV1OR2-9

Across TCGA patient cohorts, IGKV1OR2-9 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,838 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV1OR2-9-associated GO terms across cancer lineages are B cell mediated immunity, Antimicrobial humoral response, and Antibacterial humoral response. Each is linked with IGKV1OR2-9 in more than 25 cancer types. Because this analysis shows association rather than direction, both IGKV1OR2-9-to-partner and partner-to-IGKV1OR2-9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGKV1OR2-9-low versus IGKV1OR2-9-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR2-9→partner) and Y-score (partner→IGKV1OR2-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.102	+0.740	<.001	<.001	3	26
THCA	Antimicrobial humoral response →	+0.116	+0.678	<.001	<.001	3	25
THCA	Antibacterial humoral response →	+0.176	+0.684	<.001	<.001	3	25
STAD	Immunoglobulin production →	+0.077	+0.890	<.001	<.001	3	25
TGCT	Antigen receptor-mediated signaling pathway →	+0.064	+0.506	<.001	<.001	3	25
SKCM	B cell receptor signaling pathway →	+0.084	+0.388	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,838 associations by consensus.

B cell mediated immunity by IGKV1OR2-9 expression — THCA

Explore this box plot interactively →